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UNC Chapel Hill - Division of Chemical Biology and Medicinal Chemistry

Research in the Division of Chemical Biology and Medicinal Chemistry at the UNC Eshelman School of Pharmacy spans activities in contemporary chemical biology and drug discovery and blends the principles and experimental techniques of chemistry and biology with computational science. While maintaining a traditional emphasis on the drug candidate, we integrate contemporary biological methods to merge small molecule and target biomolecule research. This approach allows for elucidation of disease pathways and mechanisms of drug action. Our program encompasses nearly all aspects of drug discovery, including bioactive natural products, organic chemistry, computational drug design, assay development, high throughput screening of chemical libraries, and studies in living cells. This position is a joint appointment with the Center for Integrative Chemical Biology and Drug Discovery (CICBDD). The CICBDD was created with the mission of bringing dedicated medicinal chemistry expertise to bear on biological targets of therapeutic relevance under investigation by UNC faculty. Synthetic chemists, assay development and compound profiling scientists work in the Center and create dedicated, multidisciplinary project teams with other groups on campus in order to progress targets through the drug discovery and development process. The Center provides leadership of the North Carolina Comprehensive Chemical Biology Center, a member of NCI’s Chemical Biology Consortium.

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