A unique opportunity for a postdoctoral scholar is currently available at the Crump Institute for Molecular Imaging at the University of California Los Angeles (UCLA). Our team has joined forces with Fuzionaire Diagnostics, a Caltech spin-out company from the laboratory of Nobel Laureate Professor Bob Grubbs. The venture-backed start-up was founded by a team led by entrepreneur Nick Slavin (Yale '02, Harvard Law '05) and chemist Dr. Anton Toutov (Queen's '11, Caltech Ph.D. '16) along with an advisory team at UCLA including Professor Jennifer Murphy and Professor Michael Phelps, inventor of positron emission tomography (PET).
We are currently seeking a creative and motivated synthetic chemist ready to function in a fast-paced and collaborative environment. The synthetic chemistry candidate for this opportunity will work on novel methods for the synthesis of [18F]PET tracers to be evaluated for clinical translation at the Crump Institute for Molecular Imaging. This candidate will be part of the Murphy Group in the Crump Institute and will work closely with the Fuzionaire Diagnostics team. The goal will be to leverage a recently discovered catalytic platform to develop and optimize synthetic routes for the preparation of previously inaccessible [18F]-labeled small molecules as well as biologics such as peptides, proteins and antibodies for pre-clinical imaging studies. Experience in radiochemistry is not required; training will be provided for radiosynthesis with [18F]fluoride using automated commercial radiosynthesizers. Applicants should have exceptional communication skills coupled with a strong publication record.
* Ph.D. in organic chemistry with a strong publication record in peer-reviewed journals
* Sound knowledge of organic chemistry reactions, mechanisms, multistep synthesis, and purification techniques
* Ability to prioritize work, multi-task, and be very well organized
* Demonstrated creativity in original research and effective problem solving skills
* Awareness of safety practices required for working with hazardous chemicals
* Excellent communication skills (oral and written) with a strong work ethic
* Strong motivation to do groundbreaking, translational research along with a demonstrated ability to work efficiently and productively in a dynamic, interdisciplinary team environment
* Experience in fluorine and organometallic chemistry is highly desirable
About the Crump Institute at UCLA:
The Crump Institute provides a unique environment of translational research that aims to develop new technologies to examine the biology of disease, improve molecular diagnostic tools and advance therapeutic developments. Research focuses around positron emission tomography (PET), a powerful imaging tool that provides non-invasive, quantitative information about specific molecular targets and interactions in living organisms and patients. Molecular imaging is emerging as an essential part of cancer research and clinical care, particularly by providing tools for better understanding the biology of disease and its therapeutic modulation.
The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.
Interested applicants please send a cover letter and curriculum vitae (CV) to Prof. Jennifer Murphy at JMMurphy@mednet.ucla.edu and Dr. Anton Toutov at firstname.lastname@example.org.
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