Research Scientist - Analytical Instrumentation Specialist
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious disease. Empowered to apply our individual talents and ideas so that we can learn and grow together. Driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.
The Discovery Chemistry team is seeking a highly skilled analytical scientist with demonstrated experience in the setup and use of chromatography systems for purification of small molecules and synthetic peptides. The chosen individual will provide technical and process support for the purification and characterization of synthetic molecules using reverse phase chromatography (RPC), supercritical fluid chromatography (SFC) and automation. Self-motivation, scientific curiosity, attention to detail, and strong communication skills are required.
Specific responsibilities will include:
- Facilitating the purification of small molecules by mass-directed RPC and SFC by ensuring that appropriate processes and infrastructure are in place. This includes setup, support, troubleshooting, and root cause error analysis of laboratory equipment.
- Facilitating purification troubleshooting including method selection, scale up issues, instrument problems and software problems. Identifying common failure patterns and implement new processes to minimize future failures.
- Evaluating opportunities and collaborating with equipment vendors to integrate new analytical technologies and software into the laboratory where there is a clear benefit to implementation, such as improving process capabilities, efficiency, productivity, or quality.
- Designing and implementing new laboratory policies, methods and processes.
- Using fundamental concepts in analytical chemistry and lean work practices to identify bottlenecks, and systematically evaluate and assess root causes of errors in the laboratory,
- Collaborating with IT and automation groups to develop and enhance the capabilities of the current infrastructure and investigate future capabilities to adjust to the changing lab demands.
- BS/MS in chemistry or related field with 4-8 years of relevant pharmaceutical industry experience, or Ph.D. with 1-3 years of directly relevant industrial pharmaceutical experience.
- Solid background in separation science, including hands-on experience with operation and troubleshooting of analytical instruments, including HPLC, SFC and mass spectrometers.
- Strong computer skills, including familiarity with instrument control software and automation; programming experience is a plus.
- Strong communication and interpersonal skills to effectively interface with others working in diverse areas of expertise.