Postdoctoral Research Associate
About the Position
This postdoctoral fellowship is split into a research component and a teaching component. The research component of this postdoctoral fellowship is projected as a 0.75 full-time appointment with multiple years of guaranteed funding. The remainder of this appointment would be as an instructor, which would consist of the equivalent of teaching for one academic quarter per year in either general, organic or biochemistry. This position may be ideally suited for a postdoctoral fellow interested in a tenure-track position at a liberal arts school that values both teaching and research efforts.
Prof. P. Clint Spiegel’s laboratory investigates the structure and function of blood coagulation factor VIII and various factor VIII-containing protein complexes that exist in circulation. These efforts have resulted in detailed descriptions of the atomic structure of factor VIII, how factor VIII binds to activated platelet surfaces at the site of vascular injury, and how factor VIII is recognized by antibody inhibitors that result from hemophilia A treatment.
- Structural Biology for Antibody Recognition of Factor VIII Protein
- Perform structural biology methods including x-ray crystallography, SAXS, recombinant protein expression, purification and analysis, and generation of murine monoclonal antibody from extant hybridoma cell lines, to obtain recognition of factor VIII protein.
- Interface with collaborators who are experts in factor VIII biochemistry, hemophilia A treatment, and gene therapy approaches.
- Analyze data, summarize results
- Prepare posters and manuscripts for conferences and publications
- Supervise and assist undergraduates in the laboratory
- Assist with day-to-day management of the laboratory
- PhD in Biochemistry with a strong experimental expertise in protein biochemistry, molecular biology and/or structural biology
- Excellent written and oral communication skills.
- Ability to collaborate in a laboratory environment with undergraduate research students.
- Strong scientific writing skills and experience writing manuscripts, grants, or similar works.
- Ability to collaborate effectively with diverse students and colleagues
- Commitment to contribute to the department's mission to support underrepresented students.
- Prior experience in either X-ray crystallography or cryoelectron microscopy
- Experience with mentoring undergraduate and/or graduate students
Salary Commensurate with experience and qualifications Application Instructions
A cover letter and resume are required and should address your experience related to the position responsibilities and the required and preferred qualifications.
Please include the names and contact information of three professional references who may speak to your demonstrated laboratory experience and potential in research.
Closing Date Notes Application review begins October 6, 2018; position is open until filled