Head of Pre-clinical Informatics (Division of Pre-Clinical Innovation (DPI)

Rockville, Maryland
commensurate with experience and accomplishments
Nov 13, 2018
Jan 11, 2019
Field of specialization
Analytical, Biochemical
Job Type
Full time


The National Center for Advancing Translational Sciences (NCATS), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services is seeking applications from exceptional informatics scientists to serve as program lead for Informatics for the Division of Pre-Clinical Innovation (DPI). DPI studies translation of basic discoveries into tangible improvements to human health at a systems level as a scientific and operational problem.  The scientists within DPI come from a broad range of scientific disciplines – including, among others, therapeutic discovery, preclinical development, toxicology, biomarkers and clinical application – to reduce, remove, or bypass significant bottlenecks across the entire continuum of translation and to train the future translational science workforce.

The incumbent will serve as the Informatics Lead for NCATS intramural research.  The leader sets the informatics research agenda, leading a diverse team of data science, bioinformatics, cheminformatics, and software development professionals with discovery, preclinical development and clinical repurposing expertise to advance NCATS translational science initiatives. The position requires a strong interdisciplinary foundation in therapeutic development, genomics, mathematics, and algorithm and informatics platform development.  The leader should have a strong record of high-impact publications and experience providing tools and resources to the broader research community. The scientist in this position will serve as leader in this role and will interface with project team leads to ensure proper direction, planning, execution and completion of projects.  While ultimately accountable for delivering results, the leader achieves results through direction and appropriate delegation to assembled project teams. The incumbent will be a point person responsible for guiding and advancing collaborative projects through milestone driven practices and procedures. 

Qualifications:  Applicants must possess biomedical research or informatics training with a doctoral degree (MD, PhD or equivalent) and a record of accomplishment in preclinical translation with demonstrated experience working with multi-disciplinary research teams in technology and therapeutic/diagnostic/intervention development.  The ideal candidate will be an internationally-recognized and highly accomplished researcher in data science, clinical informatics, bioinformatics, computational chemistry or cheminformatics and familiar with all aspects of preclinical translation, with a particular interest and accomplishment in novel technology and paradigm development.  S/he must have expertise and accomplishment in multiple aspects of preclinical translation from target validation through early development of therapeutics and/or diagnostics to proof-of-concept in humans, and broad and first-hand knowledge of the field of rare disease therapeutic development, including small molecule, biologic, and gene-therapy approaches.  The candidate must have demonstrated experience working with scientifically diverse research programs, with administrative and interpersonal skills to lead a diverse workforce and to provide research and program direction.  The individual must have the ability to influence, inspire, and empower scientists and administrative staff to be creative, self-motivated, entrepreneurial achievers who deliver on the mission of the organization through individual and collaborative initiative. Finally, s/he must be a collaborative leader with demonstrated experience in engaging a broad range of stakeholders, such as scientists from different disciplines, patient advocacy groups, government agencies, and other nonprofit organizations. Open to both U.S. citizens and non-U.S. citizens.  

Salary and Benefits:   The current salary range is commensurate with experience and accomplishments; a full Civil Service package of benefits (including retirement, health, life and long term care insurance, Thrift Savings Plan participation, etc.) is available.

To Apply:

Please submit a cover letter describing your interest in the position including a career synopsis (1-3 pages); statement of research interests (1-2 pages); a current curriculum vitae and complete bibliography; and the names and contact information of three references to NCATSSSRecruit@mail.nih.gov.  Application packages will only be accepted electronically.  The position will remain open until filled. 

All information provided by candidates will remain confidential and will not be released outside the NCATS search process without a signed release from candidates. The NIH encourages the application and nomination of qualified women, minorities and individuals with disabilities.  DHHS and NIH are Equal Opportunity Employers.

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