Postdoctoral Research Associate

St. Jude Children's Research Hospital
Memphis, Tennessee
Mar 08, 2019
Apr 07, 2019
Field of specialization
Biochemical, Medicinal / Clinical
Job Type
Full time

Postdoctoral Research Associate

St. Jude Children’s Research Hospital

Memphis, TN

Postdoctoral fellowship in Medicinal Chemistry

A postdoctoral fellowship in medicinal chemistry is available in the laboratory of Dr. Richard Lee to perform structure-based drug design and synthesis of drug candidates as part of an interdisciplinary research team.  The ideal candidate will have a strong background in synthetic organic chemistry and an interest in medicinal chemistry.  The candidate will be responsible for the design and synthesis of targeted compound sets using emerging structure-activity relationships that consider both target and drug metabolism factors.  Experience in natural product synthesis, antibiotics, computer-aided drug design, fragment-based drug design, LC-MS, and NMR analysis would be advantageous.  The successful candidate must be an effective communicator and team player, keep an accurate notebook and maintain a safe working environment.

Postdoctoral trainees in the Department of Chemical Biology and Therapeutics have access to outstanding facilities for inhibitor discovery, including access to large chemical screening libraries; analytical chemistry and ADME support; high throughput and biophysical screening capabilities; high-resolution structural biology, including crystallography, NMR spectroscopy, cryo-electron microscopy.  Each fellow has in lab access to a dedicated fume hood and rotavap, electronic notebook, Biotage flash chromatography systems, state-of-the-art laboratory equipment, NMR, and UPLC-MS.

Eligibility: A recent PhD. in organic, chemical biology or medicinal chemistry is required. The successful applicant will be a good communicator in oral and written English with a track record of publication in top chemistry journals and a proven record of chemical synthesis.

Interested applicants should apply for job 39765 at

For more information, contact:

Richard E. Lee, Ph.D.

Endowed Chair in Medicinal Chemistry

Department of Chemical Biology & Therapeutics

St. Jude Children's Research Hospital

262 Danny Thomas Place, MS#1000

Memphis, TN  38105


About St Jude

Located in Memphis, Tennessee, St. Jude Children’s Research Hospital is one of the world’s premier research and treatment centers for pediatric cancers and other childhood diseases. St. Jude has been recognized by Fortune magazine as one of the “100 Best Companies to Work For” every year since 2011 and was one of The Scientist’s top 10 “Best Places to Work in Academia” for seven consecutive years. St. Jude offers highly competitive stipends and benefits and actively fosters professional development. For more information, visit

St. Jude is an Equal Opportunity Employer.