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Staff Scientist

Employer
The Scripps Research Institute
Location
La Jolla, California
Salary
Salary will be commensurate with experience
Closing date
Apr 17, 2019

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Field of specialization
Biochemical
Work Function
Laboratory, Research-Applied
Job Type
Full time

Job Details

Seeking a Staff Scientist (Ph.D. or equivalent) trained in protein biochemistry, biophysics, or chemical biology to experimentally probe the hypothesis that amyloidogenic proteins can co-populate various folds or 3-D structures upon hepatocyte secretion. Established chromatographic and novel fluorescence-based assays will be used to assess the kinetic stability of the disease-related protein, transthyretin. The candidate will perform research using a variety of molecular-biological and biochemistry techniques, including but not limited to gene cloning/mutagenesis, protein expression (E.coli), protein chromatography (FPLC, UPLC, HPLC), gel electrophoresis, and various types of optical spectroscopy (e.g. fluorescence, circular dichroism). Experience in the use of plate reader instrumentation and/or mammalian cell cultures would be considered a strong asset, but extensive training in all relevant techniques will be provided for the right candidate.

This position requires a Ph.D. degree in chemistry, biophysics or biochemistry and 2-4 years of related experience, preferentially in a fast-paced academic or biotech-industry setting. Attention to detail, confidence in handling and analyzing data, good laboratory organization and the ability to collaborate and interact productively with a variety of scientists from different scientific disciplines and at different career levels is expected. 

Company

The Scripps Research Institute (TSRI) was founded in 1961, and is one of the largest private, non-profit biomedical research facilities in the country with over 3,000 employees. At the forefront of basic biomedical science, the Institute has made major contributions to the betterment of health and the human condition. We currently have the following position available.

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