Assistant Director-Preclinical Pharmacology Core
Assistant Director – Preclinical Pharmacology Core for Accelerated Drug Discovery at The University of Texas at San Antonio
The University of Texas at San Antonio (UTSA) and the Center for Innovative Drug Discovery (CIDD) is currently seeking an experienced PhD-level scientist to serve as Assistant Director of the newly formed Preclinical Pharmacology Core for Accelerated Drug Discovery. In this role, you will have the opportunity to drive strategy and provide leadership in ADME/DMPK translational science across our diverse portfolio of current drug discovery programs within the CIDD. The position will be responsible for building a new ADME/PK core facility, establishing equipment and resources, hiring staff and establishing a robust service-oriented ADME screening platform. Your day-to-day role is to provide scientific support and guidance using various in vitro and in vivo assays to assess metabolism, permeability, CYP450 interactions and PK/PD/efficacy of early-stage small molecule preclinical candidates. You will also work closely with the CIDD Medicinal Chemistry Core Facility at UTSA and the CIDD High-Throughput Screening (HTSF) Core Facility at UT Health San Antonio to dramatically accelerate drug discovery timelines across multiple therapeutic areas including cancer, infectious diseases, neurodegenerative diseases, chronic pain and diabetes.
Qualified applicants must apply online at https://www.utsa.edu/hr/employment/ and provide a cover letter, CV/resume and three letters of recommendation.
• Ph.D. in Biological/Enzymology, Pharmaceutical Sciences/Chemistry or related field with at least 5 years of relevant ADME/DMPK pharma/biotech industry experience.
• A track record of strategic scientific leadership in the in vitro/in vivo ADME/DMPK field.
• Demonstrated experience in managing, coaching and developing scientific personnel.
• Excellent scientific communication skills as demonstrated by peer-reviewed publications, technical reports and speaking engagements.
• A strong publication record demonstrating mastery and application of drug metabolism and ADME principles.
• Expertise with LC/MS/MS techniques for API quantification and metabolite structural ID analyses.
• Familiarity working with drug discovery and development project teams.
• 10-15 years of relevant ADME/DMPK pharma/biotech industry experience.
• Experience in writing and reviewing in vitro reports for regulatory filings.
• Experience mentoring both undergraduate, graduate students and/or interns.
About UTSA and the CIDD:
The University of Texas at San Antoni (UTSA) is a rapidly growing research university with intensions to expand to 45,000 students by 2028. San Antonio, the 7th largest city in the U.S., features a beautiful, historical downtown area including the Riverwalk with its diverse entertainment and many fine restaurants. The main campus of UTSA is located northwest of downtown San Antonio adjacent to the scenic Texas Hill Country with its many recreational opportunities, local wineries and Central European influences that are unique to the area. The Center for Innovative Drug Discovery (CIDD) was founded in 2012 and has supported >75 drug discovery projects in various therapeutic areas including cancer, infectious diseases, chronic pain, neurodegeneration, diabetes and regenerative medicine. Indirectly, the CIDD has help to secure >$40 million in extramural funding with collaborating academic institutions and pharmaceutical companies. It is one of the premier academic drug discovery centers in the United States and provides ample opportunities for professional growth and career advancement for all of its staff.