The Laboratory of Protein Conformation and Dynamics in Biochemistry and Biophysics Center (BBC) of the National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health (https://www.nhlbi.nih.gov/science/protein-conformation-and-dynamics) invites applications for a Staff Scientist position. We seek a highly motivated, creative and bright individual with expertise in Raman spectral imaging, fluorescence lifetime microscopy and unnatural amino acid incorporation, who is interested in studies of amyloidogenic proteins in a range of human diseases. The NHLBI provides strong interactions with a wide range of independent research groups, and the position offers exceptional opportunities for interdisciplinary collaboration within and outside of the NIH.
The candidates must hold a Ph.D. degree or equivalent with at least 3 years of postdoctoral experience. A proven track record of productivity judged by peer reviewed publications is required. The successful candidate must have a strong background in vibrational spectral imaging and fluorescence lifetime imaging. Expertise in incorporation of unnatural amino acids into proteins using genetic code expansion in bacterial systems, as well as methods for protein purification including ion exchange chromatography and affinity chromatography are highly desired. Experience in mammalian cell culture and viral transfection will be viewed favorably. Specialized experience and publications of interest could include Raman spectral imaging, vibrational spectroscopy of proteins, and amyloid formation.
The successful candidate will have an opportunity to conduct innovative and independent research in amyloid formation and amyloid-cell interactions, in a supportive setting, with access to extensive existing and newly acquired Raman and fluorescence lifetime imaging microscopy equipment. It is expected that the candidate will take an active role in supporting other members in the Lab and will participate in cooperative, team-based efforts to accomplish program, division, and Institute goals. Responsibilities will include but not limited to instrumentation maintenance and development, lab supplies management, lab safety practices, purchasing and inventory management. The successful candidate will be offered a competitive salary commensurate with experience and qualifications.
The initial appointment will be for a minimum of 2 years, with possible appointment renewals in 1-year increments. Appointees must be US citizens, resident aliens, or nonresident aliens with a valid employment visa.
The research is funded by the intramural research program and does not require applications for grants or external support.
Applicants should submit a cover letter highlighting key qualifications and long term career goals, a current curriculum vitae with complete bibliography, and three reference letters (via email only) to:
Administrative Officer, NHLBI
The review of applications will begin on rolling basis as complete application packages are submitted. Applications will be accepted until the position is filled.
HHS and NIH are Equal Opportunity Employers. Positions are subject to a background check. Applications from women, minorities and persons with disabilities are strongly encouraged to apply. The NHLBI/NIH is a smoke free workplace.