Senior Research Scientist, Analytical R&D

Arvinas Inc
New Haven, Connecticut
Up to $120,000 pear year + benefits
Closing date
Dec 8, 2021

View more

Field of specialization
Work Function
Technical Services
Job Type
Full time
You need to sign in or create an account to save a job.

Arvinas is a clinical-stage biopharmaceutical company leading the way in targeted protein degradation therapeutics. Arvinas is the first company to focus solely on protein degradation and its platform technology is the most advanced in the field. Since its founding in 2013, Arvinas’ PROTAC® Discovery Engine has been driving the most significant breakthroughs in the industry. Arvinas’ pipeline encompasses a range of validated and undruggable targets in oncology, immuno-oncology, and neuroscience. This includes two clinical-stage programs: ARV-110, which is being developed as a potential treatment for men with late-line metastatic castrate-resistant prostate cancer, and ARV-471, which is being developed as a potential treatment for patients with breast cancer.

#TeamArvinas is made up of more than 200 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and purpose – to improve the well-being of patients and families impacted by the devastating diseases Arvinas is working to treat. It’s an exciting time to be in drug development and it’s an exciting time to be at Arvinas. But don’t just take our word for it – here’s what Arvinas employees are saying. For more information, please visit

Position Summary

We are currently seeking an analytical chemist to join the Analytical Research and Development organization within Technical Operations at Arvinas. The incumbent will serve as a core member of a multidisciplinary project team and directly impact execution of the analytical programs for both active pharmaceutical ingredient and drug product development and manufacturing. The qualified individual will have a track record of accomplishment in analytical method development, conducting complex analytical investigations. This position will work closely with the members of Chemical Process Development, Formulation R&D, and External Manufacturing and Supply. In addition, the incumbent will work closely with project teams to develop and execute a streamlined program to advance assets into clinic and then into commercialization. The incumbent will ensure all activities occur in compliance with the appropriate SOPs and regulations.

This position reports to the Director, Analytical R&D and will be located at our headquarters in New Haven, CT.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

  • Set up/develop (U)HPLC methods to support in-house activities in process chemistry and formulation group
  • Conduct laboratory-based analytical investigations to trouble-shoot complex analytical problems using H/UPLC, LC/MS, NMR, DSC, TGA and PXRD.
  • Provide technical insight to contracted suppliers in execution of analytical-related deliverables, including phase-appropriate method development and validation.
  • Manage, review analytical data and reports, track release, stability, and reference material testing, and lead laboratory investigations along with QA. Analyze stability trends through statistical and scientific tools.
  • Working with External Manufacturing and Supply select the best providers of service to meet project needs.
  • Facilitate the collection of relevant analytical data and reports from suppliers and contribute to drafting of INDs, NDAs, and associated amendments.
  • Provide management of in-house analytical instruments.
  • Evaluate quotes from vendors and recommend instrument acquisition as subject expert.
  • Communicate analytical workplans and strategies with functional group leaders to ensure project timelines are met.


  • A successful history of hands-on analytical investigations and method development for small molecule (U)HPLC achiral and chiral methods
  • Strong understanding of spectroscopy, NMR, and mass spectrometery.
  • Experience with solid state analysis is a plus.
  • A competent grasp of organic chemistry and functional group reactivity.
  • Ability to effectively prioritize and deliver on tight timelines
  • Outstanding problem-solving abilities
  • Detail-oriented, with good organizational and project management skills
  • Good oral and written communications skills
  • Proficient with MS Word, PowerPoint, Excel
  • Strong project planning, and presentation skills
  • Ability to multi-task and manage several projects in parallel, paying attention to detail.
  • Ability to forge cross-functional working relationships with internal and external project partners
  • Ability to be proactive in identifying issues and hurdles that may hinder the effective progression of an asset and resolve the issues in a timely and creative fashion


PhD in Analytical Chemistry or related technical field with 2-5 years of related experience, which may include post – doctoral work.

You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalised job recommendations straight to your inbox.

Create alert