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Metabolomics Systems Computational Scientist - 4084

Richland, Washington State
Closing date
Jun 18, 2022

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Job Details

Pacific Northwest National Laboratory (PNNL) is a world-class research institution powered by a highly educated, diverse workforce committed to the values of Integrity, Creativity, Collaboration, Impact, and Courage. Every year, scores of dynamic, driven people come to PNNL to work with renowned researchers on meaningful science, innovations and outcomes for the U.S. Department of Energy and other sponsors; here is your chance to be one of them!

At PNNL, you will find an exciting research environment and excellent benefits including health insurance, flexible work schedules and telework options. PNNL is located in eastern Washington State—the dry side of Washington known for its stellar outdoor recreation and affordable cost of living. The Lab’s campus is only a 45-minute flight (or ~3 hour drive) from Seattle or Portland, and is serviced by the convenient PSC airport, connected to 8 major hubs.

The Computational Biology Group at the Pacific Northwest National Laboratory (PNNL) is seeking a Metabolomics Systems Computational Scientist to join our team and lead in the development of new research proposals with strong expertise in computational biology including modeling of complex chemical processes in microbes and microbial communities; biophysics and predictive biology; and software development.


The Metabolomic Systems Computational Scientist will contribute to diverse fundamental science research programs studying DOE relevant systems for biofuels/bioproducts, organism/microbial and human health problems such as cancer and infectious diseases. The candidate will be responsible for computational and data science method development, and work directly in interdisciplinary teams including chemists, bioinformaticians, computer scientists, data scientists and software developers. The position involves working with advanced computing platforms, developing new algorithms, applying statistical analysis, and data integration methods that will be used to develop models to account for complex interactions between biosystems and their associated metabolites. The incumbent will define and carry out the application of existing methodologies, as well as perform original research in the field of computational biology. In addition to technical research, the incumbent will lead and participate in publishing, project leadership, and business development.

Minimum Qualifications:

  • BS/BA with 5 years of experience
  • MS/MA with 3 years of experience
  • PhD with 1 year of experience

Preferred Qualifications:

  • Experience with metabolic modeling in bacteria
  • Use of data (multi-omics and/or phenotypic data) to constrain metabolic models
  • Analysis of microbiome data to inform community metabolic models
  • Development of novel algorithms for metabolic analysis and modeling
  • Dynamic and/or population-based models for microbiome modeling
  • Familiarity with coding and software development best practices and high performance computing



For more information and/or to apply, please visit:    

Questions? Please contact Kim Willer at           


At PNNL, we deliver breakthrough science and technology to meet key national needs. We also apply our capabilities to meet selected environmental, energy, health and national security objectives, strengthen the economy, and support the education of future scientists and engineers. PNNL is managed by DOE's Office of Science, but we perform work for many DOE offices as well as other government agencies. Battelle has operated PNNL for DOE and its predecessors since 1965. A unique feature of Battelle's contract with DOE allows our staff to work for private industry. Pacific Northwest National Laboratory - Fiscal Year 2004 Business Statistics Business Volume and Customers Our business volume was $638 million. Customers included the U.S. Department of Energy and other federal, state and local agencies; universities; and industry sponsors. Awards In FY 2004, PNNL received four R&D 100 Awards, for a total of 66. PNNL has won a total of 58 Federal Laboratory Consortium awards for technology transfer. PNNL has also won: 5 EO Lawrence Awards 1 Coblentz Award 4 Discover Magazine Awards. For more information on PNNL awards, see Patents In FY 2004, PNNL received 63 U.S. and 44 foreign patents. Since 1965, PNNL has received a total of 1,217 U.S. and foreign patents. Employment, Payroll and Taxes Staff employment at the end of FY 2004 was 3,900. The gross payroll for the year was approximately $279.5 million. Employer-paid benefits totaled $52.4 million and various state and federal payroll taxes paid by the Laboratory amounted to more than $21 million. The Laboratory also paid: $1.6 million in business and occupation taxes $838,000 in sales and use taxes $1.1 million in property and leasehold taxes. Purchased Goods and Services PNNL purchased goods and services totaling more than $250 million. Economic Development PNNL's economic development programs helped more than 50 technology businesses develop products, acquire new customers and contracts, get access to funding sources and strategic partners, and secure specialized facilities and staff. The U.S. Department of Commerce selected PNNL as a national model of technology-based economic development among 300 federal laboratories.
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