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Post-Doctoral Research Associate

University of Texas Health Science Center at Tyler
Tyler, Texas
$50,000 +
Closing date
Dec 13, 2022

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Field of specialization
Biochemical, Biological, Microbiological
Work Function
Job Type
Full time

A virology-biophysics lab at the University of Texas Health Science Center, Tyler (UTHSCT) is now seeking one highly motivated postdoc in biophysics/biochemistry to join the team. The principal investigator has a strong research record in single-molecule imaging of HIV-1 and SARS-CoV-2 surface spikes (Lu et al., 2019, Nature, 568: 415-419; Lu et al., 2020, Cell Host & Microbe, 28: 880-891. e8; mBio, 2022 Mbio 13 (1), e03227-21, The research spectrum of the lab falls into the dynamics-structure-function paradigm of crucial proteins on enveloped viruses, focusing on how viruses modulate their surface spike proteins to evade antibody recognition while mediating the entry of viruses into susceptible cells for infection. The lab is working on HIV-1 and SARS-CoV-2, and has interest in branching out to other viruses as well.

UTHSCT provides full-time postdoctoral fellows very competitive fringe benefits, such as retirement plans and health insurance coverages across UT Health in-network systems. Postdoctoral fellows are expected to be semi-independent in constructing research projects under the supervision of the PI.

Successful candidates should have one or more areas of experience as below:

  • Single-molecule FRET or single-molecule biophysics (strongly encouraged to apply)
  • Biophysics/Biochemistry/Structural biology skills: protein expression, protein purification, SPR, programing experiences (desirable, but not required), etc. (strongly encouraged to apply)
  • Hands-on experience in biomedical imaging, such as confocal, TIRF, time-resolved fluorescence, TCSPC, etc.
  • Molecular biology skills: molecular cloning, western blots, ELISA, qPCR, etc.
  • Lentiviruses, coronaviruses, or other infectious diseases


  • To lead specific projects, perform experiments, analyze data, and interpret results
  • To present results at scientific conferences, prepare manuscripts, and publish findings in peer-reviewed journals.
  • To communicate well with other lab members and collaborators.


  • Doctoral degree (PhD) in one of the life sciences or optics/imaging-related fields
  • Comfortable to work collaboratively and interdisciplinary.

To Apply:

Please email a cover letter explaining relevant work experience, a CV, and the names and contact information for three references to A short list of candidates will be directly contacted by the PI.

Maolin Lu, PhD

Assistant Professor of Cellular and Molecular Biology

The University of Health Science Center at Tyler

11937 U.S. Hwy 271, Tyler, TX 75708

Telephone: (903) 877-8738



As an Equal Opportunity Employer, the University will, in accordance with State and Federal law and regulations, provide equal opportunity in all employment related activities without regard to race, color, religion, national origin, gender, age, disability, sexual preference, or status as a disabled veteran or a veteran of the Vietnam Era.  The University requires pre-employment drug & alcohol screening, proof of COVID-19 vaccination and/or medical or religious exemption, and health immunizations and criminal background check on all hires. Specific job requirements or physical location of some positions allocated to this classification, may render this position security sensitive, and thereby subject to the provisions of Section 51.215, Texas Education Code

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