Research Associate in Pharmaceutical Engineering
- University of Texas at Austin
- Austin, Texas
- Closing date
- Feb 25, 2023
- Field of specialization
- Work Function
- Job Type
- Full time
The College of Pharmacy, Division of Molecular Pharmaceutics and Drug Delivery is seeking a Research Associate for Dr. Bill Williams' lab.
Additional hours may be required during peak periods. Occasional travel may be required.
A Research Associate in Pharmaceutical Engineering and thin-film freezing-drying in the Williams' Lab at the Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy (a top 4 Pharmacy college in the USA), The University of Texas at Austin.
Will work on project(s) to develop advanced powder manufacturing technologies and applications using our proprietary thin-film freezing-drying process with biologics. The successful candidate will develop and optimize advanced freezing and biologics stabilization processes. The candidate should have expertise through their publication record and work experience on ultra-rapid freezing of biologics, characterization of biologics (e.g., monoclonal antibodies, mRNA, mRNA/lipid nanoparticles, plasmid DNA, siRNA, peptides, therapeutic proteins).
Conduct research in the broad area of pharmaceutics and drug delivery including ultra-rapid freezing-drying on biological molecules
Attend regular collaborative meetings with the industrial project partners and collaborators to identify any potential areas of future collaboration.
Write proposals for industry sponsored research agreements and technology validation agreements in collaboration with PI.
Develop innovative and patentable ideas that use ultra-rapid freezing-drying applied to a wide variety of materials, including pharmaceutical and biotechnology compositions.
Involved in mentoring graduate students and undergraduate students as appropriate.
Disseminate the experimental results at national and international conferences. Present research outputs to wider community in the form of podium/oral presentation. Engage with the relevant stakeholders, collaborators and sponsors.
Write and publish research papers and review papers on results generated in the laboratory.
Contribute to grant proposal writing based on the primary results obtained from the project as deemed necessary by the PI.
Other duties as assigned.
PhD in pharmaceutics, pharmaceutical engineering or Biomedical/Chemical Engineering received within the last 4 years or equivalent scholarly or relevant professional activity.
Equivalent combination of relevant education and experience may be substituted as appropriate.
At least 2 years' work experience in pharmaceutics or biotechnology
Extensive experience with freezing-drying technologies (thin-film freezing and spray-freeze drying) applied to biological molecules intended for medical or pharmaceutical products
Skills in peptide and protein analysis, both chemical and physical (MFI, DLS, SEC-HPLC, CD, SDS-PAGE, ELISA)
Skills in nucleic acid (mRNA, DNA) delivery system analysis (Entrapment efficiency assay, agarose gel)
Extensive skills and experience on surface activity phenomenon of biological compounds (Pendant/Du Nuoy tensiometer)
Skills and experience in Design of Experiments (DOE) using linear regression model, and artificial neural network.
Experience and knowledge in pharmaceutical formulations for inhalation, nasal delivery and injectable delivery.
Skills and experience in physicochemical characterization of dry powder (DSC, SAXS/WAXS, XRD, SEM, BET, DVS)
Skills and experience in applied chemistry, related to bio-conjugation (e.g., fluorescent tagging of biomolecules) and drug-excipient interaction (FTIR, NMR)
Experience in engineering, capable of prototyping simple thermoelectric cooling device for freezing small amount of samples
Experience in handling of liquid nitrogen and other cryogenic materials
$59,000 + depending upon qualifications
May work around standard office conditions.
May work around biohazards.
May work around chemicals.
3 work references with their contact information
Letter of interest
Applicants may apply here: https://apptrkr.com/3836569
Important for applicants who are NOT current university employees or contingent workers: You will be prompted to submit your resume the first time you apply, then you will be provided an option to upload a new Resume for subsequent applications. Any additional Required Materials (letter of interest, references, etc.) will be uploaded in the Application Questions section; you will be able to multi-select additional files. Before submitting your online job application, ensure that ALL Required Materials have been uploaded. Once your job application has been submitted, you cannot make changes.
Important for Current university employees and contingent workers: As a current university employee or contingent worker, you MUST apply within Workday by searching for Find UT Jobs. If you are a current University employee, log-in to Workday, navigate to your Worker Profile, click the Career link in the left hand navigation menu and then update the sections in your Professional Profile before you apply. This information will be pulled in to your application. The application is one page and you will be prompted to upload your resume. In addition, you must respond to the application questions presented to upload any additional Required Materials (letter of interest, references, etc.) that were noted above.
Regular staff who have been employed in their current position for the last six continuous months are eligible for openings being recruited for through University-Wide or Open Recruiting, to include both promotional opportunities and lateral transfers. Staff who are promotion/transfer eligible may apply for positions without supervisor approval.
Retirement Plan Eligibility:
The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length. This position has the option to elect the Optional Retirement Program (ORP) instead of TRS, subject to the position being 40 hours per week and at least 135 days in length.
A criminal history background check will be required for finalist(s) under consideration for this position.
Equal Opportunity Employer:
The University of Texas at Austin, as an http://www.utexas.edu/equity/about/presidents-statement, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.
The University of Texas at Austin will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information.
Employment Eligibility Verification:
If hired, you will be required to complete the federal Employment Eligibility Verification I-9 form. You will be required to present acceptable and original http://hr.utexas.edu/current/services/I9docs.html to prove your identity and authorization to work in the United States. Documents need to be presented no later than the third day of employment. Failure to do so will result in loss of employment at the university.
The University of Texas at Austin use E-Verify to check the work authorization of all new hires effective May 2015. The university's company ID number for purposes of E-Verify is 854197. For more information about E-Verify, please see the following:
• http://www.utexas.edu/hr/documents/EverifyPosterEnglish.pdf [PDF]
• http://www.utexas.edu/hr/documents/EverifyPosterSpanish.pdf [PDF]
• http://www.utexas.edu/hr/documents/RightToWorkPosterEnglish.pdf [PDF]
• http://www.utexas.edu/hr/documents/RightToWorkPosterSpanish.pdf [PDF]
Employees may be required to report violations of law under Title IX and the Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act (Clery Act). If this position is identified a Campus Security Authority (Clery Act), you will be notified and provided resources for reporting. Responsible employees under Title IX are defined and outlined in https://policies.utexas.edu/policies/prohibition-sexual-discrimination-sexual-harassment-sexual-assault-sexual-misconduct.
The Clery Act requires all prospective employees be notified of the availability of the Annual Security and Fire Safety report. You may https://compliance.utexas.edu/sites/default/files/documents/Annual%20Security%20and%20Fire%20Safety%20Report.pdf or obtain a copy at University Compliance Services, 1616 Guadalupe Street, UTA 2.206, Austin, Texas 78701.
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