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Postdoctoral Fellow, Medicinal Chemistry

National Center of Advancing Translational Services
Rockville, Maryland
commensurate with experience
Closing date
Jun 10, 2023

View more

Field of specialization
General / Technical
Work Function
Job Type
Full time


NCATS, a major research component of NIH, is seeking a highly motivated synthetic chemist to serve as a postdoctoral fellow for drug discovery projects within the Therapeutic Development Branch (TDB) of its Division of Preclinical Innovation. The selected candidate will work on a multidisciplinary team to identify clinical candidates to address unmet medical needs.

The TDB partners with collaborators (academic institutions, foundations, and private industry) to implement preclinical development studies leading to investigational New Drug (IND) applications for new therapeutics. These projects play a leading role in the NCATS mission to develop new ways to reduce, remove or bypass bottlenecks across the entire continuum of translational science, and to address rare and neglected diseases.

Core Responsibilities

The postdoctoral fellow will be responsible for designing and synthesizing compounds for structure-activity relationship and structure-property relationship studies, developing new technologies to accelerate drug discovery, presenting results in internal and external meetings, and writing reports and manuscripts. The research will be conducted in the TDB medicinal chemistry group.


Applicants should have (or expect to receive) a Ph.D. in organic chemistry or medicinal chemistry at the time of joining the laboratory. The ideal candidate should be self-motivated, possess a strong work ethic, have a keen attention to detail, and be able to work on multiple projects simultaneously. The candidate should possess strong oral and written communication skills with a proven publication record in peer-reviewed journals. Applicants should be eligible to work in the United States for any employer.


The current salary range is commensurate with experience in accordance with the NIH Postdoctoral Intramural Research Training Award and Visiting Fellow Stipend Ranges for All Areas; health insurance benefits are available. The fellow can take part in Foundation for Advanced Education in the Sciences courses at the NIH as well.

How to Apply

Please submit a cover letter describing your interest in the position, including a research summary, a current curriculum vitae; and the names of and contact information for three references to Wenwei Huang, Ph.D., via

The review of applications will begin immediately and will continue until the position is filled. Learn more about intramural research at NCATS.

Additional Information

Employment is subject to the successful completion of the pre-appointment process (e.g., background investigation, verification of qualifications and job requirements, completion of onboarding forms, submission of required documents).

At the discretion of the supervisor and NIH policy, you may be eligible for workplace flexibilities, which may include remote work or telework options and/or flexible work scheduling. These flexibilities may be requested in accordance with the NIH Workplace Flexibilities policy.


The NIH is dedicated to building a diverse community in its training and employment programs.





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